Wednesday, April 25, 2018

Study reveals the inner workings of a molecular motor that packs and unpacks DNA

Precision, complexity, organization, heavy duty, astounding , react rapidly to alterations in their environment - all through BUC.

The more we learn the harder it is for evo proponents to advocate with a straight face. It looks designed but we know it isn’t. :grinning:

Study reveals the inner workings of a molecular motor that packs and unpacks DNA
Moreover, the entire DNA must be replicated before cell division and DNA damage needs to be repaired.

This is when chromatin remodelers come into play. Chromatin remodelers have an essential role as they are molecular machines: they unpick and unpack segments of the DNA by sliding nucleosome spools back and forth, replacing individual histones, freeing up the DNA for transcription, and finally compacting it again, when the job is done. Since all of this happens in a highly dynamic fashion, chromatin remodelers enable cells to react rapidly to alterations in their environment – and this holds for brewer’s yeast as well as for human cells. In mediating gene accessibility, chromatin remodelers are vital for development and cell differentiation; cell types are defined by the sets of genes they express, remodelers help to determine cell identity.

From a biochemical point of view, remodelers are responsible for heavy-duty reorganizational tasks. To perform these tasks, they must execute “large-scale conformational changes, which are carried out with astounding precision,”


 phys.org

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