Denis Noble explains his revolutionary theory of genetics | Genes are not the blueprint for life

Denis Noble explains his revolutionary theory of genetics | Genes are not the blueprint for life

Human and chimp Y chromosomes are very different - Horrendously Different

Human and chimp Y chromosomes are very different - Horrendously Different

The death of NeoDarwinism, No Selfish Gene

"The genome... is best described as a database used by organisms to generate the functions that you and I and others study as physiology."

"We inherit much more than DNA"

"The number of possible interactions , the number of possible circuits you could form 25,000 genes is 10^70,000. There wouldn't be enough time over the whole billions of years of the evolution of life on earth for nature to have explored but more than a tiny fraction of those."


On Dawkins and the selfish gene - "He is totally confused."    "He has misused a metaphor"  "He [Dawkins] is philosophically naive and  I am afraid he has misled many people for a very considerable period of  time."  40 minutes in

"There are no good or bad genes"

"There are reasons those genes are there"

"The great majority of people we are talking to were educated in biology 30 or 40 years ago and they really have no idea of the sea change that has occurred."


"the house of cards, the citadel if you like  is empty, but many people still do not know that."  54 min

(more in comments below...)

Past 5,000 years prolific for changes to human genome

 

A study published today in Nature³ now helps to clarify when many of those rare variants arose. Researchers used deep sequencing to locate and date more than one million single-nucleotide variants — locations where a single letter of the DNA sequence is different from other individuals — in the genomes of 6,500 African and European Americans. The findings confirm their earlier work suggesting that the majority of variants, including potentially harmful ones, were picked up during the past 5,000–10,000 years. Researchers also saw the genetic stamp of the diverging migratory history of the two groups.

Human Genome in Meltdown

A previous post here - Dr. John Sanford "Genetic Entropy and the Mystery of the Genome" Below is additional support for IDvolution. Some quotes from Dr John Sanford on genetic entropy. Very consistent with IDvolution and Scripture. To get the full effect take the time to view the videos. Listen carefully where he states it is "kind of a trade secret of population geneticists." The design of the genome is astonishing and shows intelligence, design and purpose. "We are not some casual and meaningless product of evolution. Each of us is a thought of God."Pope Benedict XVI

and now we have this in Nature. Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants 86% arose in the last 5-10,000 years.

A new definition of species

I had predicted this a number of times before.  As we study genetics further we will find a better way to classify species.  Alas, here we have a new paper that

Proteins and Genes, Singletons and Species

Recent experimental data from proteomics and genomics are interpreted here in ways that challenge the predominant viewpoint in biology according to which the four evolutionary processes, including mutation, recombination, natural selection and genetic drift, are sufficient to explain the origination of species. The predominant viewpoint appears incompatible with the finding that the sequenced genome of each species contains hundreds, or even thousands, of unique genes – the genes that are not shared with any other species. These unique genes and proteins, singletons, define the very character of every species. Moreover, the distribution of protein families from the sequenced genomes indicates that the complexity of genomes grows in a manner different from that of self-organizing networks: the dominance of singletons leads to the conclusion that in living organisms a most unlikely phenomenon can be the most common one. In order to provide proper rationale for these conclusions related to the singletons, the paper first treats the frequency of functional proteins among random sequences, followed by a discussion on the protein structure space, and it ends by questioning the idea that protein domains represent conserved units of evolution.

Designed changes vs random changes

This paper shows that some "mutations" are designed changes directed by cellular machinery.

Genomic "tuning knobs" with implicit range are strategies for organisms to change and adapt as needed.  We know about fine tuning in the universe, now we see it in life.

Remember the Genetic Piano post (here)?  Which keys are chosen to play?   What decides?


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and

How Bees Decide What to Be: Reversible 'Epigenetic' Marks Linked to Behavior Patterns

and

Harvard cracks DNA storage, crams 700 terabytes of data into a single gram -Must see.....

and

Is There Enough Time For Humans to have Evolved from Apes? Dr. Ann Gauger

Dr. John Sanford "Genetic Entropy and the Mystery of the Genome"

Below is additional support for IDvolution.

Some quotes from Dr John Sanford on genetic entropy. Very consistent with IDvolution and Scripture.  To get the full effect take the time to view the videos.  Listen carefully where he states it is "kind of a trade secret of population geneticists."  The design of the genome is astonishing and shows intelligence, design and purpose.  

"We are not some casual and meaningless product of evolution. Each of us is a thought of God."Pope Benedict XVI  

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"a vastly superior operating system"

"a galaxy of design and complexity"

"over 90% of the genome is actively transcribed"

"the genome has multiple overlapping messages"

"data compression on the most sophisticated level"

"more and more the genome looks like a super super set of programs"

"more and more it looks like top down design"

"the reality is everybody is mutant"

"the selection process really has nothing to grab hold of"

"so it's kind of a trade secret amongst population geneticists,any well informed population geneticist understands man is degenerating"

"so in deep geological time we should have been extinct a long time ago"

"the human race is degenerating at 1-5% per generation"

"so personal and so immediate, because there is no circle of life where things where things stay the same, and it's not an upward spiral of evolution, things keep getting better and better, it is a downward spiral exactly as described in Scripture"

"I realized it had major implications for evolution, but I had no... I couldn't have guessed how profound the biblical implications are, how profoundly the evidence supports the biblical perspective of a dying universe and a dying world, we are dying because of the fall"

"and our only hope is Christ"

Dr. John Sanford "Genetic Entropy and the Mystery of the Genome"1/2

Dr. John Sanford "Genetic Entropy and the Mystery of the Genome" 2/2