Tuesday, February 19, 2019

Cell-Directed Mutations

Cell-Directed Mutations

This video shows the evidence that, rather than being entirely haphazard, cells can direct their own mutations. This means that evolution is a regulated cellular process, just like any other bodily function.


Friday, August 17, 2018

Sweeping gene survey reveals new facets of evolution

More evidence for IDvolution.

Sweeping gene survey reveals new facets of evolution

It is textbook biology, for example, that species with large, far-flung populations—think ants, rats, humans—will become more genetically diverse over time.
But is that true?
"The answer is no," said Stoeckle, lead author of the study, published in the journal Human Evolution.
For the planet's 7.6 billion people, 500 million house sparrows, or 100,000 sandpipers, genetic diversity "is about the same," he told AFP.
The study's most startling result, perhaps, is that nine out of 10 species on Earth today, including humans, came into being 100,000 to 200,000 years ago.
"This conclusion is very surprising, and I fought against it as hard as I could," Thaler told AFP.

Read more at: https://phys.org/news/2018-05-gene-survey-reveals-facets-evolution.html#jCp
It is textbook biology, for example, that species with large, far-flung populations—think ants, rats, humans—will become more genetically diverse over time.

But is that true?

"The answer is no," said Stoeckle, lead author of the study, published in the journal Human Evolution.

For the planet's 7.6 billion people, 500 million house sparrows, or 100,000 sandpipers, genetic diversity "is about the same," he told AFP.

The study's most startling result, perhaps, is that nine out of 10 species on Earth today, including humans, came into being 100,000 to 200,000 years ago.

"This conclusion is very surprising, and I fought against it as hard as I could," Thaler told AFP.

It is textbook biology, for example, that species with large, far-flung populations—think ants, rats, humans—will become more genetically diverse over time.
But is that true?
"The answer is no," said Stoeckle, lead author of the study, published in the journal Human Evolution.


Read more at: https://phys.org/news/2018-05-gene-survey-reveals-facets-evolution.html#jCp
It is textbook biology, for example, that species with large, far-flung populations—think ants, rats, humans—will become more genetically diverse over time.
But is that true?
"The answer is no," said Stoeckle, lead author of the study, published in the journal Human Evolution.


Read more at: https://phys.org/news/2018-05-gene-survey-reveals-facets-evolution.html#jCp
It is textbook biology, for example, that species with large, far-flung populations—think ants, rats, humans—will become more genetically diverse over time.
But is that true?
"The answer is no," said Stoeckle, lead author of the study, published in the journal Human Evolution.
For the planet's 7.6 billion people, 500 million house sparrows, or 100,000 sandpipers, genetic diversity "is about the same," he told AFP.
The study's most startling result, perhaps, is that nine out of 10 species on Earth today, including humans, came into being 100,000 to 200,000 years ago.
"This conclusion is very surprising, and I fought against it as hard as I could," Thaler told AFP.


Read more at: https://phys.org/news/2018-05-gene-survey-reveals-facets-evolution.html#jCp
 
It is textbook biology, for example, that species with large, far-flung populations—think ants, rats, humans—will become more genetically diverse over time.
But is that true?
"The answer is no," said Stoeckle, lead author of the study, published in the journal Human Evolution.


Read more at: https://phys.org/news/2018-05-gene-survey-reveals-facets-evolution.html#jCp
“another unexpected finding from the study—species have very clear genetic boundaries, and there’s nothing much in between."

“If individuals are stars, then species are galaxies,” said Thaler. “They are compact clusters in the vastness of empty sequence space.”

The absence of “in-between” species is something that also perplexed Darwin, he said."

Read more at: https://phys.org/news/2018-05-gene-survey-reveals-facets-evolution.html#jCp

 

"If individuals are stars, then species are galaxies," said Thaler. "They are compact clusters in the vastness of empty sequence space."
The absence of "in-between" species is something that also perplexed Darwin, he said.


Read more at: https://phys.org/news/2018-05-gene-survey-reveals-facets-evolution.html#jCp

Sweeping gene survey reveals new facets of evolution

Wednesday, April 25, 2018

Study reveals the inner workings of a molecular motor that packs and unpacks DNA

Precision, complexity, organization, heavy duty, astounding , react rapidly to alterations in their environment - all through BUC.

The more we learn the harder it is for evo proponents to advocate with a straight face. It looks designed but we know it isn’t. :grinning:

Study reveals the inner workings of a molecular motor that packs and unpacks DNA
Moreover, the entire DNA must be replicated before cell division and DNA damage needs to be repaired.

This is when chromatin remodelers come into play. Chromatin remodelers have an essential role as they are molecular machines: they unpick and unpack segments of the DNA by sliding nucleosome spools back and forth, replacing individual histones, freeing up the DNA for transcription, and finally compacting it again, when the job is done. Since all of this happens in a highly dynamic fashion, chromatin remodelers enable cells to react rapidly to alterations in their environment – and this holds for brewer’s yeast as well as for human cells. In mediating gene accessibility, chromatin remodelers are vital for development and cell differentiation; cell types are defined by the sets of genes they express, remodelers help to determine cell identity.

From a biochemical point of view, remodelers are responsible for heavy-duty reorganizational tasks. To perform these tasks, they must execute “large-scale conformational changes, which are carried out with astounding precision,”


 phys.org

The clouds of spaghetti that keep DNA data safe

The clouds of spaghetti that keep DNA data safe

Cells can avoid “data breaches” when letting signaling proteins into their nuclei thanks to a quirky biophysical mechanism involving a blur of spaghetti-like proteins, researchers from the Rockefeller University and the Albert Einstein College of Medicine have shown. Their study appears in the March 23 issue of the Journal of Biological Chemistry.

In every human cell, all of the body’s blueprints and instructions are stored in the form of DNA inside the nucleus. Molecules that need to travel in and out of the nucleus – to turn genes on or off or retrieve information – do so through passageways called nuclear pore complexes (NPCs). Traffic through these NPCs must be tightly controlled in order to prevent DNA hijacking by viruses or faulty functioning as in cancer.

"How on Earth do you have the kind of specificity that we see in protein-protein interactions like antibodies, and yet have the kind of speed that we see with water off a Teflon pan?"

"I can’t think of any analogy in normal life that does what this does," Rout said. "You’ve got this blur of (amino acids) coming on and off (the transport factor) with extraordinary speed."


Sunday, December 24, 2017

Royal Society Meeting - Modern Synthesis is Broken

Read a report on the Royal Society Meeting
“The Modern Synthesis, while undoubtedly productive for a time, is a misconception of reality that has reached the limits of its explanatory power. The problems are fundamental. No amount of cosmetic surgery is going correct them.”
“To the contrary, Darwinian competition causes not the evolution of species but the destruction of species.It is collaboration in its various forms that causes biological evolution. Hence I’m surprised by calls for extending the neo-Darwinian Evolutionary Synthesis. You can’t extend something that is broken. Surely what is needed now, after 65 years, is using the empirical evidence to develop a new paradigm for biological evolution.”
"If you want the definition of the Modern Synthesis, take a look at how Neil deGrasse Tyson explains evolution in the 2014 remake of Carl Sagan’s Cosmos series. Tyson, an astrophysicist, is unaware that he is misinformed, as are most in science, academia, government, literature, the arts, and the public by this outmoded theory of evolution."
“Shuker tried to interrupt but Noble held his ground:
‘No, YOU need to listen. I used to think exactly like you. I embraced the reductionist mindset for years. When I got out of school I was a card-carrying reductionist. Reductionism is powerful and it’s useful. I am not dissing it. Many times we need it. But it is not the whole story.’ Noble described how bacterial regulatory
networks rebuilt those genes in four days by hyper-mutating, actively searching for a solution that would give them tails and enable them to Nind food. Natural selection did not achieve that. Natural genetic engineering did.’”
“It’s appropriate that this meeting is being held at the Royal Society, whose motto, we were reminded yesterday, is “Nullius in verba”: Accept nothing on authority."
“Not one whit of empirical evidence shows that new species arise from the neo-Darwinian mechanism. To the contrary, Darwinian competition causes not the evolution of species but the destruction of species.”